Inopantin belongs to the group of gastrointestinal drugs, dosage form of soft capsule, box of 10 blisters x 10 tablets. The main component of the drug is arginine hydrochloride 300 mg. Patients follow the following article to find out what Inopantin. For approved drug preparations and parenteral applications in the treatment of amanite fungus poisoning, water-soluble disodium salt of silibinin-C-2`,3-dihyrogensuccinate is used. In 2011, the same active substance was also designated as an orphan drug by the European Commission for the prevention of recurrent hepatitis C in liver transplant recipients. [14] Legalon contains the active substance silymarin, which is derived from the milk thistle plant. Its main action is to protect liver cells from the harmful effects of various factors such as alcohol, drugs, viral infections and industrial pollutants. It also provides powerful natural antioxidant properties that contribute to the overall well-being of the body.* Silibin is available as a drug (Legalon SIL (Madaus) (D, CH, A) and Silimarit (Bionorica), a silymarin product) in many EU countries and is used to treat toxic liver damage (e.g. IV treatment for deadly plug poisoning); as adjunctive therapy for chronic hepatitis and cirrhosis.
[ref. needed] Hepatic pathology, both viral and non-viral (alcoholic hepatitis, fatty liver, etc.), is widely used in Georgia. In such cases, the diagnosis of the disease and the correct treatment strategy are very important, since hepatotropic drugs play an important role. A modern physician, infectious hepatologist or gastroenterologist relies on evidence-based medicine. 40 years of experience of Legalon in the global market and the current benefits of researching this multifunction. The above article gives a detailed description of the important role of drugs in the pathogenic treatment of liver diseases of viral and non-viral etemology (alcoholic, toxic, etc.). Legalon becomes more interesting because the process of implementing its injection form is underway and the need to use the injection form is highlighted by the results of the latest international studies. The article describes the latest research presented at the special satellite conference held at the European Association for the Study of the Liver`s Annual International Congress on the Liver in Berlin in 2011 (April-March). Silymarin, like other flavonoids, has been shown to inhibit P-glycoprotein-mediated cell efflux.[8] Modulation of P-glycoprotein activity may result in impaired absorption and bioavailability of drugs that are substrates of P-glycoprotein. Silymarin has been reported to inhibit cytochrome P450 enzymes and interaction with drugs primarily removed from P450 cannot be excluded. [9] By supporting normal excretory processes in the body1,3,4 Due to its immunomodulatory,[19] iron-chelating and antioxidant properties, this herb has the potential to be used in beta-thalassemia patients who receive regular blood transfusions and suffer from iron overload. [20] In Legalon, care is taken to use the same specific milk thistle extract, known as MZ 80, which has been produced in a patented production process and studied in clinical trials to support healthy liver function.1-8 Legalon® contains a proprietary extract of the plant, Silybum marianum, better known as milk thistle.
The specific extract used in Legalon – known as MZ 80 – is produced using a patented manufacturing process and has been extensively researched in clinical and scientific studies over the past decades.1-8 Thuốc Bidalic có công dụng trong điều trị viêm gan cấp và mạn tính do virus, Rượu, Thuốc, gan nhiễm mỡ và rối loạn chức năng. Để dùng thuốc Amtim an toàn và hiệu quả thì bạn nên tham khảo. Adults: Take 1 capsule 3 times daily or as directed by a healthcare practitioner. To calculate the total number of stars and the percentage distribution per star, we do not use a simple average. Instead, our system takes into account things like updating a review and whether the reviewer purchased the item on Amazon. It also analyzed reviews to check for reliability. The symptoms of liver injury are not specific and the damage is often overlooked.5,11 The biosynthesis of silibin A and silibin B consists of two main parts, taxifolin and coniferyl alcohol. [22] [23] Coniferyl alcohol is synthesized in the shell of milk thistle seeds. Starting with the conversion of phenylalanine to cinnamic acid, mediated by phenylalanine ammonia lyase.
[24] Cinnamic acid then undergoes two oxidation cycles with trans-cinnamon-4-monooxygenase and 4-coumarate-3-hydroxylase to obtain caffeic acid. Metaposition alcohol is methylated by caffeic acid 3-O-methyltransferase to produce ferulic acid. From ferulic acid, coniferyl alcohol is produced by 4-hydroxycinnamon-CoA ligase, cinnamyl CoA reductase and cinnamon alcohol dehydrogenase. For taxifolin, its biosynthesis genes in flowers may be overexpressed because transcription depends on light. The production of taxifolin uses a pathway similar to that used for the synthesis of p-coumaric acid, followed by a triple extension of the carbon chain with malonyl-CoA and cyclization by chalcon synthase and chalcon isomerase to naringenin. Taxifolin is provided by flavanone-3-hydroxylase and flavonoid 3`-monooxygenase. In order to fuse taxifolin and coniferyl alcohol, taxifolin can be transferred from the flower to the seed shell via the Symplast pathway. Taxifolin and coniferyl alcohol are oxidized by ascorbate peroxidase 1 to allow the mono-electron reaction to couple two fragments that produce silybin (silibin A + silibin B). The only registered silymarin supplement in South Africa12 Your doctor can help you decide if Legalon is right for you. It`s always best to discuss all your symptoms with your doctor to determine if Legalon is a suitable option for you and how to use it.
To find out more about this study, you or your doctor can contact the study`s research staff using the contact information provided by the sponsor. There are no known interactions between Legalon and other medicines. As always, it is recommended to speak to your doctor if you have any questions about using Legalon. For consumers: Legalon is available from naturopaths, major pharmacies and health food stores or can be ordered directly from us on our website. Food for thought: Did you know that a stressed liver can cause fatigue? Learn more about how Legalon can help support liver health. LEGALON® FORTE: A unique and patented silymarin supplement that nourishes your liver.12, 13, 14, 15 Legalon is not recommended during pregnancy or breastfeeding, as there are no published studies proving its safe use during pregnancy or breastfeeding.
